Hodgkin's lymphoma patients fail to establish an efficient cellular response against CD30 +
Hodgkin/Reed-Sternberg cells. An impaired T-cell receptor/CD3-ζ-mediated activation of T …

Introduction Gender as a predictor of outcomes of rheumatoid arthritis (RA) has evoked
considerable interest over the decades. Historically, there is no consensus whether RA is worse …

Objective Regular physical activity is associated with decreased morbidity and mortality.
Traditionally, patients with rheumatoid arthritis (RA) have been advised to limit physical exercise…

Introduction Work disability is a major consequence of rheumatoid arthritis (RA), associated
not only with traditional disease activity variables, but also more significantly with …

Objective To assess the determinants of patients' (PTGL) and physicians' (MDGL) global
assessment of rheumatoid arthritis (RA) activity and factors associated with discordance among …

Objective. People with RA have episodes of worsening disease activity (flares) that prompt
them to seek clinical review or medication change. This study explored patients’ perspectives …

Background Several controlled studies provide evidence that treatment with interferon beta
in patients with a first event suggestive of multiple sclerosis (MS) delays conversion to …

Importance It remains unclear whether vitamin D insufficiency, which is common in
individuals with multiple sclerosis (MS), has an adverse effect on MS outcomes. Objectives To …

Background The aim of the Betaferon Efficacy Yielding Outcomes of a New Dose (BEYOND)
trial was to compare the efficacy, safety, and tolerability of 250 μg or 500 μg interferon beta-…

Background In most patients, severity of valvular aortic stenosis can be accurately assessed
non-invasively by echocardiography. However, retrograde catheterisation of the aortic valve …