The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting,
and appraisal. However, trial protocols and existing protocol guidelines vary greatly in …

Purpose To determine whether adding shear-wave (SW) elastographic features could improve
accuracy of ultrasonographic (US) assessment of breast masses. Materials and Methods …

Objectives To evaluate intra- and interobserver reproducibility of shear wave elastography (SWE)
for breast masses. Methods For intraobserver reproducibility, each observer obtained …

Background: Hepatic steatosis is associated with obesity and type II diabetes. Proton magnetic
resonance spectroscopy ( 1 H MRS) is a non-invasive method for measurement of tissue …

Background Rivaroxaban is established for the treatment and secondary prevention of venous
thromboembolism, but whether it is useful in patients with antiphospholipid syndrome is …

Background Adjustment for prognostic covariates can lead to increased power in the analysis
of randomized trials. However, adjusted analyses are not often performed in practice. …

BACKGROUND: The purpose of this study was to determine the cerebrovascular risk
stratification potential of baseline degree of stenosis, clinical features, and ultrasonic plaque …

Colony-forming units of Mycobacterium tuberculosis in sputum were counted at 2-day intervals
in 100 patients treated with 22 regimens of isoniazid, rifampin, pyrazinamide, ethambutol, …

The quantity and distribution of adipose tissue are markers of morbidity risk. The third trimester
of human development is a period of rapid adipose tissue deposition. Preterm infants may …

PURPOSE: The role of thyroxine replacement in subclinical hypothyroidism remains unclear.
We performed a 6-month randomized, double-blind, placebo-controlled trial to evaluate the …