Pressure reversal of narcosis produced by anaesthetics, narcotics and tranquillisers

MJ Halsey, B Wardley-Smith - Nature, 1975 - nature.com
THE first demonstration of pressure reversal of anaesthesia in amphibians was provided by
the tadpole experiments of Johnson and Flagler 1 with ethanol and ethyl carbamate. Since …

Treatment with parathyroid peptides and estrogen replacement for severe postmenopausal vertebral osteoporosis: prediction of long-term responses in spine and …

…, M Tellez, P Hulme, JR Green, B Wardley-Smith… - Journal of bone and …, 2001 - Springer
Fifteen women with severe vertebral osteoporosis were treated with daily parathyroid peptide
(hPTH) plus hormone-replacement co-therapy (HRT) for 1 year. Eight other patients were …

Occupational exposure to anaesthetics in 20 hospitals

HT Davenport, MJ Halsey, B WARDLEYSMITH… - …, 1980 - Wiley Online Library
The nitrous oxide and halothane contamination in the inspired air of anaesthetists and in
the atmospheres of operating theatres, anaesthetic induction and recovery rooms, were …

Gamma-aminobutyric acid and the high pressure neurological syndrome

JC Rostain, B Wardley-Smith, C Forni, MJ Halsey - Neuropharmacology, 1986 - Elsevier
Sodium valproate, nipecotic acid, diaminobutyric acid (DABA) and beta-adanine are drugs
which enhance transmission mediated by γ-aminobutyric acid (GABA) by a variety of …

Effect of excitatory amino acid antagonists on the high pressure neurological syndrome in rats

B Wardley-Smith, BS Meldrum - European journal of pharmacology, 1984 - Elsevier
The onset pressures for the tremor, myoclonus and convulsions seen in the high pressure
neurological syndrome (HPNS) are increased following cis-2,3-piperidine dicarboxylic acid 1 …

The effects of non-competitive NMDA receptor antagonists on rats exposed to hyperbaric pressure

B Wardley-Smith, KT Wann - European journal of pharmacology, 1989 - Elsevier
The high pressure neurological syndrome (HPNS) occurs when man or animals are exposed
to hyperbaric pressure. Four non-competitive N-methyl-D-aspartate (NMDA) antagonists - …

High pressure and intravenous steroid anesthesia in rats

…, MJ Halsey, B Wardley-Smith - Journal of Applied …, 1977 - journals.physiology.org
Anesthesia produced by the intravenous steroid agent, Althesin, was studied in Sprague-Dawley
rats with and without high pressure of helium gas up to 100 atmospheres absolute (ATA…

Specific effects of drugs at pressure: animal investigations

…, JC Rostain, B Wardley-Smith - … of the Royal …, 1984 - royalsocietypublishing.org
… The preliminary results of this investigation (Wardley-Smith et al. 1981) suggest that opioid
receptors play only a minor role, if any, in hpns, and it is clear that morphine exacerbates …

Mechanism of inhibition of bacterial luciferase by anaesthetics

G Adey, B Wardley-Smith, D White - Life sciences, 1975 - Elsevier
The effects of volatile anaesthetics on bacterial luciferase were studied in vitro . It was shown
that the concentration of anaesthetic required to inhibit the reaction velocity by 50% was …

Pressure reversal of the effect of urethane on the evoked somatosensory cortical response in the rat.

…, MJ Halsey, B Wardley-Smith - British Journal of …, 1980 - ncbi.nlm.nih.gov
The cerebral response evoked by stimulation of the forepaw in the rat shows an increase in
latency and decrease in the amplitude of its initial components as anaesthetic dose (urethane…