Musculoskeletal ultrasound including definitions for ultrasonographic pathology.

…, G Bruyn, D Kane, PJ O'Connor, B Manger… - The Journal of …, 2005 - jrheum.org
Ultrasound (US) has great potential as an outcome in rheumatoid arthritis trials for detecting
bone erosions, synovitis, tendon disease, and enthesopathy. It has a number of distinct …

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

…, Y Zhao, D Kienhöfer, B Frey, M Lell, B Manger… - Nature medicine, 2014 - nature.com
Gout is characterized by an acute inflammatory reaction and the accumulation of neutrophils
in response to monosodium urate (MSU) crystals. Inflammation resolves spontaneously …

Sustained benefits of infliximab therapy for dermatologic and articular manifestations of psoriatic arthritis: results from the infliximab multinational psoriatic arthritis …

…, E Keystone, D Gladman, B Manger… - Arthritis & …, 2005 - Wiley Online Library
Objective To investigate the efficacy and tolerability of infliximab therapy for the articular and
dermatologic manifestations of active psoriatic arthritis (PsA). Methods One hundred four …

Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus

I Baumann, W Kolowos, RE Voll, B Manger… - Arthritis & …, 2002 - Wiley Online Library
Objective To investigate the fate of apoptotic cells in the germinal centers (GCs) of patients
with systemic lupus erythematosus (SLE). Methods Lymph node biopsy specimens obtained …

CD19-targeted CAR T cells in refractory systemic lupus erythematosus

…, S Kharboutli, S Böltz, B Manger… - … England Journal of …, 2021 - Mass Medical Soc
CAR T Cells for Refractory Systemic Lupus Erythematosus A 20-year-old woman with
refractory SLE with active lupus nephritis (WHO class IIIA), nephrotic syndrome, pericarditis, …

Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies

A Kleyer, S Finzel, J Rech, B Manger… - Annals of the …, 2014 - ard.bmj.com
Objective Anticitrullinated protein antibodies (ACPA) are a major risk factor for bone loss in
rheumatoid arthritis (RA). We have recently shown that ACPA directly induce bone loss by …

[HTML][HTML] Mortality in rheumatoid arthritis: the impact of disease activity, treatment with glucocorticoids, TNFα inhibitors and rituximab

J Listing, J Kekow, B Manger, GR Burmester… - Annals of the …, 2015 - ard.bmj.com
Objectives To investigate the impact of disease activity, the course of the disease, its
treatment over time, comorbidities and traditional risk factors on survival. Methods Data of the …

[HTML][HTML] COVID-19 revisiting inflammatory pathways of arthritis

G Schett, B Manger, D Simon, R Caporali - Nature Reviews …, 2020 - nature.com
Coronavirus disease 2019 (COVID-19) is an infectious disease, caused by severe acute
respiratory syndrome coronavirus 2, which predominantly affects the lungs and, under certain …

SARS-CoV-2 vaccination responses in untreated, conventionally treated and anticytokine-treated patients with immune-mediated inflammatory diseases

…, S Kleinert, AJ Hueber, K Manger, B Manger… - Annals of the …, 2021 - ard.bmj.com
Objectives To better understand the factors that influence the humoral immune response to
vaccination against SARS-CoV-2 in patients with immune-mediated inflammatory diseases (…

Interleukin-1 function and role in rheumatic disease

G Schett, JM Dayer, B Manger - Nature Reviews Rheumatology, 2016 - nature.com
Interleukin (IL)-1, first described∼ 35 years ago as a secreted product of monocytes and
neutrophils, refers to IL-1α and IL-1β, two key cytokines in the activation of innate immunity. …