[HTML][HTML] Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493 737 UK Biobank …

P Hanlon, BI Nicholl, BD Jani, D Lee… - The Lancet Public …, 2018 - thelancet.com
Background Frailty is associated with older age and multimorbidity (two or more long-term
conditions); however, little is known about its prevalence or effects on mortality in younger …

[HTML][HTML] Ethnic and socioeconomic differences in SARS-CoV-2 infection: prospective cohort study using UK Biobank

…, BD Jani, E Demou, FK Ho, C Celis-Morales, BI Nicholl… - BMC medicine, 2020 - Springer
Background Understanding of the role of ethnicity and socioeconomic position in the risk of
developing SARS-CoV-2 infection is limited. We investigated this in the UK Biobank study. …

Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants

…, F Ho, B Jani, DF Mackay, B Nicholl… - Occupational and …, 2021 - oem.bmj.com
Objectives To investigate severe COVID-19 risk by occupational group. Methods Baseline
UK Biobank data (2006–10) for England were linked to SARS-CoV-2 test results from Public …

[HTML][HTML] Prevalence and characteristics of probable major depression and bipolar disorder within UK biobank: cross-sectional study of 172,751 participants

DJ Smith, BI Nicholl, B Cullen, D Martin, Z Ul-Haq… - PloS one, 2013 - journals.plos.org
Objectives UK Biobank is a landmark cohort of over 500,000 participants which will be used
to investigate genetic and non-genetic risk factors for a wide range of adverse health …

[HTML][HTML] The effect of socioeconomic deprivation on the association between an extended measurement of unhealthy lifestyle factors and health outcomes: a …

HME Foster, CA Celis-Morales, BI Nicholl… - The Lancet Public …, 2018 - thelancet.com
Background Combinations of lifestyle factors interact to increase mortality. Combinations of
traditional factors such as smoking and alcohol are well described, but the additional effects …

[HTML][HTML] Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci

…, CR Gale, SJ Ritchie, C Hayward, B Nicholl… - Molecular …, 2016 - nature.com
Neuroticism is a personality trait of fundamental importance for psychological well-being and
public health. It is strongly associated with major depressive disorder (MDD) and several …

Effectiveness of app-delivered, tailored self-management support for adults with lower Back pain–related disability: a selfBACK randomized clinical trial

…, MJ Stochkendahl, BI Nicholl… - JAMA internal …, 2021 - jamanetwork.com
Importance Lower back pain (LBP) is a prevalent and challenging condition in primary care.
The effectiveness of an individually tailored self-management support tool delivered via a …

[HTML][HTML] Digital support interventions for the self-management of low back pain: a systematic review

BI Nicholl, LF Sandal, MJ Stochkendahl… - Journal of medical …, 2017 - jmir.org
Background Low back pain (LBP) is a common cause of disability and is ranked as the most
burdensome health condition globally. Self-management, including components on …

[HTML][HTML] Relationship between multimorbidity, demographic factors and mortality: findings from the UK Biobank cohort

BD Jani, P Hanlon, BI Nicholl, R McQueenie… - BMC medicine, 2019 - Springer
Background Multimorbidity is associated with higher mortality, but the relationship with
cancer and cardiovascular mortality is unclear. The influence of demographics and type of …

[HTML][HTML] Genome-wide association study of multisite chronic pain in UK Biobank

KJA Johnston, MJ Adams, BI Nicholl, J Ward… - PLoS …, 2019 - journals.plos.org
Chronic pain is highly prevalent worldwide and represents a significant socioeconomic and
public health burden. Several aspects of chronic pain, for example back pain and a severity-…