Background GCA is a large vessel vasculitis affecting older people, with the highest incidence
among persons 70–79 years of age [1]. Due to forecasted demographic changes, it has …

Objectives To perform a systematic review of neurologic involvement in Systemic sclerosis (SSc)
and Localized Scleroderma (LS), describing clinical features, neuroimaging, and …

Highlights • Type I IFN is implicated in SLE pathogenesis by multiple lines of evidence,
including genetics and induction of SLE by IFN treatment. • Nucleic-acid sensing pathways …

Objective To develop new antiphospholipid syndrome (APS) classification criteria with high
specificity for use in observational studies and trials, jointly supported by the American …

This paper presents an open, multi-vendor, multi-field strength magnetic resonance (MR) T1-weighted
volumetric brain imaging dataset, named Calgary-Campinas-359 (CC-359). The …

The Tumor Necrosis Factor-alpha (TNF-α) is a pleiotropic cytokine that produces different
stimuli in various physiological and pathological conditions. TNF-α contributes importantly to …

Objective: To evaluate the frequency and risk factors of epileptic seizures in a large cohort
of patients with systemic lupus erythematosus (SLE). Methods: Five hundred nineteen …

Background The literature regarding clinical olfaction, olfactory loss, and olfactory dysfunction
has expanded rapidly over the past two decades, with an exponential rise in the past year. …

Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease,
represents a significant challenge for both diagnosis and treatment. Patients with SLE in …

The relationship between depression and immunity has been widely discussed. Cytokines,
such as TNF-α, play an important role in immune system; these cytokines interact with …