Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus
erythematosus (SLE). Although SLE is—by and large—a systemic disease, occasionally it …

Our objective was to update the EULAR recommendations for the management of systemic
lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic …

Objective To update the 2012 EULAR/ERA–EDTA recommendations for the management of
lupus nephritis (LN). Methods Following the EULAR standardised operating procedures, a …

Background Low disease activity is a validated target of current systemic lupus erythematosus
(SLE) therapy. The aim of this study was to assess the ability of belimumab to achieve low …

Objective. To compare the European League Against Rheumatism (EULAR) recommendations
for the management of NPSLE with usual care in two tertiary centres and to detect …

SLE poses formidable therapeutic challenges due to its heterogeneity and treatment
decisions often cannot be guided by data of high quality. In this review, we attempt to provide …

We have begun to better understand how brain-reactive autoantibodies, present in a
proportion of SLE patients, can cause brain injury and diffuse NPSLE. Further testing will be …

Stroke is a major cause of morbidity, mortality and disability in systemic lupus erythematosus
(SLE). Patients with SLE have a two-fold increase in the risk of stroke with younger patients (…

Cells | Free Full-Text | Pathogenic and Therapeutic Relevance of JAK/STAT Signaling in
Systemic Lupus Erythematosus: Integration of Distinct Inflammatory Pathways and the Prospect …

Objectives To update the EULAR recommendations for the management of systemic lupus
erythematosus (SLE) based on emerging new evidence. Methods An international Task …