Methods. All patients had participated in the 56-week COBRA trial. During followup, they were
seen by their own rheumatologists and were also assessed regularly by study nurses; no …

Objective. To assess the efficacy of low-dose pred-nisolone on joint damage and disease
activity in patients with early rheumatoid arthritis (RA). Methods. At the start of their initial …

Background The value of intensive combination therapy in early rheumatoid arthritis is
unproven. In a multicentre, double-blind, randomised trial (COBRA), we compared the …

Objectives Uveitis, psoriasis and inflammatory bowel disease (IBD) are common extra-articular
manifestations (EAM) in patients with ankylosing spondylitis (AS); however, summary …

Objective To summarize the prevalence of spondyloarthritis (SpA) and its subtypes in the
general population, and to identify demographic and methodologic characteristics that might …

Objectives We investigated access to biologic and synthetic disease modifying drugs (bDMARDs
and sDMARDs) in patients with rheumatoid arthritis (RA) across Europe. Methods A …

Objectives. Although clinicians recognize hip involvement, which frequently leads to hip
replacement surgery, as an important feature of AS, data on the epidemiology, nature of the …

Background TNF (tumor necrosis factor)‐alpha inhibitors block a key protein in the
inflammatory chain reaction responsible for joint inflammation, pain, and damage in ankylosing …

Background Tight and personalised control of inflammatory bowel disease in a traditional
setting is challenging because of the disease complexity, high pressure on outpatient clinics, …

The acute as well as chronic clinical features of ankylosing spondylitis (AS) are a burden to
the patient and society. Apart from the axial and articular manifestations, extraarticular AS-…