Measurement of arterial wall thickness as a surrogate marker for atherosclerosis

…, GK Hovingh, A Wiegman, P Duriez, AJ Smit… - Circulation, 2004 - Am Heart Assoc
Large observational studies and atherosclerosis regression trials of lipid-modifying pharmacotherapy
have established that intima-media thickness of the carotid and femoral arteries, as …

Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients

…, JW Baynes, G Navis, ROB Gans, AJ Smit - Journal of the …, 2005 - journals.lww.com
Tissue advanced glycation end products (AGE) are a measure of cumulative metabolic stress
and trigger cytokines driven inflammatory reactions. AGE are thought to contribute to the …

Advanced glycation end‐products (AGEs) and heart failure: pathophysiology and clinical implications

…, AA Voors, SJL Bakker, AJ Smit… - European journal of …, 2007 - Wiley Online Library
Advanced glycation end‐products (AGEs) are molecules formed during a non‐enzymatic
reaction between proteins and sugar residues, called the Maillard reaction. AGEs accumulate …

Skin autofluorescence is a strong predictor of cardiac mortality in diabetes

…, R Graaff, JW Baynes, ROB Gans, AJ Smit - Diabetes …, 2007 - Am Diabetes Assoc
OBJECTIVE—Advanced glycation end products (AGEs) are biomarkers of metabolic stress
and are thought to contribute to the increase of coronary heart disease (CHD) in diabetes. …

ROC analysis of noninvasive tests for peripheral arterial disease

…, JJAM van den Dungen, J Loonstra, AJ Smit - Ultrasound in medicine …, 1996 - Elsevier
The purpose of this study is to evaluate the diagnostic accuracy of selected noninvasive tests
for assessing peripheral arterial disease. The ankle/brachial index (ABI) and the femoral …

Skin autofluorescence as a noninvasive marker of vascular damage in patients with type 2 diabetes

…, LJ Ubink-Veltmaat, HJ Bilo, RO Gans, AJ Smit - Diabetes …, 2006 - Am Diabetes Assoc
OBJECTIVE—Advanced glycation end products (AGEs) are thought to have a role in the
pathogenesis of diabetes complications. We recently reported the association between skin …

[HTML][HTML] Effect of an increased intake of α-linolenic acid and group nutritional education on cardiovascular risk factors: the Mediterranean Alpha-linolenic Enriched …

WJE Bemelmans, J Broer, EJM Feskens, AJ Smit… - The American journal of …, 2002 - Elsevier
Background: The effect of long-term increased intakes of α-linolenic acid (ALA; 18:3n−3) on
cardiovascular risk factors is unknown. Objectives: Our objectives were to assess the effect …

Measurements of carotid intima-media thickness and of interadventitia common carotid diameter improve prediction of cardiovascular events: results of the IMPROVE …

…, F Veglia, U de Faire, SE Humphries, AJ Smit… - Journal of the American …, 2012 - jacc.org
Objectives : The goal of this study was to compare the performance of several measures of
carotid intima-media thickness (C-IMT) as predictors of cardiovascular events (CVEs), and to …

Skin autofluorescence: a tool to identify type 2 diabetic patients at risk for developing microvascular complications

…, N Kleefstra, R Graaff, KH Groenier, AJ Smit… - Diabetes …, 2008 - Am Diabetes Assoc
OBJECTIVE—Skin autofluorescence is a noninvasive measure of the level of tissue accumulation
of advanced glycation end products, representing cumulative glycemic and oxidative …

Skin autofluorescence, a novel marker for glycemic and oxidative stress-derived advanced glycation endproducts: an overview of current clinical studies, evidence …

…, R Graaff, RO Gans, F Zijlstra, AJ Smit - Diabetes technology …, 2006 - liebertpub.com
Background: Advanced glycation endproducts (AGEs) predict long-term complications in
agerelated diseases. However, there are no clinically applicable markers for measuring AGEs …