Demyelinating disease in patients treated with TNF antagonists in rheumatology: data from BIOBADASER, a pharmacovigilance database, and a systematic review

…, A Naranjo, C Esteban, AM Ortiz… - Seminars in arthritis and …, 2011 - Elsevier
OBJECTIVES: To estimate the rate of demyelinating diseases in patients with rheumatic
diseases treated with tumor necrosis factor (TNF) antagonists and to describe the cases …

Consensus statement on a framework for the management of comorbidity and extra-articular manifestations in rheumatoid arthritis

…, F Romero, JA Martínez-López, AM Ortiz… - Rheumatology …, 2015 - Springer
The objective of the study was to develop evidence-based and practical recommendations
for the detection and management of comorbidity in patients with rheumatoid arthritis (RA) in …

Clinical features and 123I-FP-CIT SPECT imaging in vascular parkinsonism and Parkinson's disease

…, F Carrillo, AM Ortiz, M Carballo… - Journal of Neurology …, 2013 - jnnp.bmj.com
Objectives To analyse the differences in the clinical features and characteristics of 123 I-labelled
2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl) nortropane ( 123 I-FP-CIT) …

2014 update of the Consensus Statement of the Spanish Society of Rheumatology on the use of biological therapies in rheumatoid arthritis

…, E Martín-Mola, VM Martínez-Taboada, AM Ortiz… - … Clínica (English Edition), 2015 - Elsevier
Objective To establish recommendations for the management of patients with rheumatoid
arthritis (RA) to serve as a reference for all health professionals involved in the care of these …

[PDF][PDF] Rapid beneficial effect of the IL-6 receptor blockade on insulin resistance and insulin sensitivity in non-diabetic patients with rheumatoid arthritis

…, I Llorente, E Aurrecoechea, AM Ortiz… - Clin Exp …, 2019 - wiredspace.wits.ac.za
Objective In patients with rheumatoid arthritis (RA), insulin resistance (IR), a component of
the metabolic syndrome, is closely linked to the systemic inflammation induced by …

[HTML][HTML] Seven-chain adaptive immune receptor repertoire analysis in rheumatoid arthritis reveals novel features associated with disease and clinically relevant …

…, M Alperi-López, J Tornero, AM Ortiz… - Genome Biology, 2024 - Springer
Background In rheumatoid arthritis (RA), the activation of T and B cell clones specific for self-antigens
leads to the chronic inflammation of the synovium. Here, we perform an in-depth …

Baseline serum RANKL levels may serve to predict remission in rheumatoid arthritis patients treated with TNF antagonists

I González-Alvaro, AM Ortiz, EG Tomero… - Annals of the …, 2007 - ard.bmj.com
Aims: The objective of this study was to investigate whether baseline receptor activator for
nuclear factor kappaB ligand (RANKL) and osteoprotegerin (OPG) serum (s) levels can predict …

[HTML][HTML] Increased albumin oxidation in cerebrospinal fluid and plasma from Alzheimer's disease patients

M Costa, R Horrillo, AM Ortiz, A Pérez… - Journal of …, 2018 - content.iospress.com
Background: Oxidative stress in the brain and peripheral systems is considered a major
player in Alzheimer’s disease (AD). Albumin is the main transporter and the main extracellular …

[HTML][HTML] Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-κB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility

…, B Fernandez-Gutierrez, AM Ortiz… - Arthritis research & …, 2009 - Springer
Introduction Genome-wide association studies of rheumatoid arthritis (RA) have identified an
association of the disease with a 6q23 region devoid of genes. TNFAIP3, an RA candidate …

Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross‐Disease Meta‐Analysis of Genome …

…, A Balsa, AM Ortiz… - Arthritis & …, 2016 - Wiley Online Library
Objective Systemic sclerosis (SSc) and rheumatoid arthritis (RA) are autoimmune diseases
that have similar clinical and immunologic characteristics. To date, several shared SSc–RA …