The identification and management of interstitial lung disease in systemic sclerosis: evidence-based European consensus statements

…, B Griffiths, A Guillén-Del-Castillo… - The Lancet …, 2020 - thelancet.com
Background Systemic sclerosis-associated interstitial lung disease (ILD) carries a high
mortality risk; expert guidance is required to aid early recognition and treatment. We aimed to …

COVID-19 in solid organ transplantation: a matched retrospective cohort study and evaluation of immunosuppression management

…, JM Del-Rio-Gutiérrez, A Guillén-Del-Castillo… - …, 2021 - journals.lww.com
Background. The epidemiological and clinical characteristics of solid organ transplant (SOT)
patients during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Cardiac involvement in systemic sclerosis: differences between clinical subsets and influence on survival

…, MN Pizzi, CE Hidalgo, AG Del Castillo… - Rheumatology …, 2017 - Springer
Cardiac involvement (CI) is a known complication of SSc associated with increased mortality.
Our objective was to describe a cohort of patients with SSc and CI and to assess the …

Novel risk factors related to cancer in scleroderma

D Bernal-Bello, JG de Tena, A Guillén-del Castillo… - Autoimmunity …, 2017 - Elsevier
Objective Emerging data have shown an increased risk of malignancy among patients
diagnosed with systemic sclerosis (SSc) so identification of risk factors linking both disorders …

Digital ulcers and cutaneous subsets of systemic sclerosis: Clinical, immunological, nailfold capillaroscopy, and survival differences in the Spanish RESCLE Registry

…, M Freire-Dapena, A Guillén-del Castillo… - Seminars in arthritis and …, 2016 - Elsevier
Objective Digital ulcers (DU) are the most common vascular complication of systemic sclerosis
(SSc). We compared the characteristics between patients with prior or current DU with …

First clinical symptom as a prognostic factor in systemic sclerosis: results of a retrospective nationwide cohort study

…, C Tolosa-Vilella, A Guillen-del Castillo… - Clinical …, 2018 - Springer
The objective of the study is to determine the importance of the mode of onset as prognostic
factor in systemic sclerosis (SSc). Data were collected from the Spanish Scleroderma …

[PDF][PDF] Clinical and epidemiological differences between men and women with systemic sclerosis: a study in a Spanish systemic sclerosis cohort and literature review

…, C Tolosa Vilella, A Guillen-Del Castillo… - Clin Exp …, 2017 - researchgate.net
Objective. The low overall prevalence of systemic sclerosis (SSc) and the low proportion of
male patients have resulted in a scarcity of studies assessing sex differences in Ssc patients, …

[HTML][HTML] Standardized incidence ratios and risk factors for cancer in patients with systemic sclerosis: Data from the Spanish Scleroderma Registry (RESCLE)

C Carbonell, M Marcos, A Guillén-Del-Castillo… - Autoimmunity …, 2022 - Elsevier
Aim Patients with systemic sclerosis (SSc) are at increased risk of cancer, a growing cause
of non–SSc-related death among these patients. We analyzed the increased cancer risk …

Autoantibodies to stratify systemic sclerosis patients into clinically actionable subsets

…, L Beretta, CP Simeón, A Guillén-Del-Castillo… - Autoimmunity …, 2020 - Elsevier
Systemic sclerosis (SSc) is a rare chronic disease of unknown etiology characterized by
vascular abnormalities and fibrosis involving the skin and internal organs, especially the …

[HTML][HTML] Quantitative videocapillaroscopy correlates with functional respiratory parameters: a clue for vasculopathy as a pathogenic mechanism for lung injury in …

A Guillén-Del-Castillo, CP Simeón-Aznar… - Arthritis research & …, 2018 - Springer
Background To determine whether lung involvement is related to microvascular perturbations,
nailfold videocapillaroscopy (NVC) was performed in patients with systemic sclerosis (SSc…