The 1,852,442-bp sequence of an M1 strain of Streptococcus pyogenes, a Gram-positive
pathogen, has been determined and contains 1,752 predicted protein-encoding genes. …

BACKGROUND Modern reproductive behavior in most developed countries is characterized
by delayed parenthood. Older gametes are generally less fertile, accumulating and …

Purpose This phase III international study compared the efficacy and safety of a combination
of pegylated liposomal doxorubicin (PLD) plus bortezomib with bortezomib monotherapy in …

STUDY QUESTION Are preconception phthalate and phthalate replacements associated with
sperm differentially methylated regions (DMRs) among men undergoing IVF? SUMMARY …

The chromosome of group B streptococci (GBS) contains a gene which is related to the C5a
peptidase gene (scpA) of group A streptococci (GAS). scpA encodes a surface-associated …

Sex-dependent pituitary growth hormone (GH) secretory profiles—pulsatile in males and
persistent in females—regulate the sex-biased, STAT5-dependent expression of hundreds of …

STUDY QUESTION Is sperm epigenetic aging (SEA) associated with probability of pregnancy
among couples in the general population? SUMMARY ANSWER We observed a 17% …

Modern humans have populated Europe for more than 45,000 years 1 , 2 . Our knowledge of
the genetic relatedness and structure of ancient hunter-gatherers is however limited, owing …

Background Currently, the precise mechanisms that underline male infertility are still unclear.
Accumulating data implicate non‐coding RNA cargo of seminal plasma extracellular …

A multidisciplinary group of experts gathered in Parma Italy for a workshop hosted by the
University of Parma, May 16–18, 2014 to address concerns about the potential relationship …