As indicators of responsiveness to a tumour necrosis factor (TNF)α blocking agent (infliximab)
are lacking in rheumatoid arthritis, we have used gene profiling in peripheral blood …

Background: Rheumatoid arthritis (RA) is associated with systemic bone loss, subchondral
bone erosion and cartilage degradation under the control of pro-inflammatory cytokines, …

OBJECTIVE: To suggest recommendations for management of acute infusion reactions
induced by infliximab in patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA). …

Polymerase chain reaction (PCR) amplification, which is a useful method for detecting
infectious agents in joints, has potential utility in the molecular diagnosis of venereal‐associated …

Tumour necrosis factor (TNF)-α plays a key role in the pathogenesis of rheumatoid arthritis (RA).
It binds to two receptors, namely TNF receptor (TNFR)I and TNFRII. Several studies …

Objectives To evaluate the benefits for rheumatoid arthritis (RA) patients of switching from
one tumor necrosis factor inhibitor (TNFi) to another based on reason for change (primary …

Objectives. The overall non-response rate to biologics remains 30–40% for patients with RA
resistant to MTX. The objective of this study was to predict responsiveness to the anakinra–…

Objective To validate the 2010-ACR/EULAR criteria for rheumatoid arthritis (RA), taking into
account the recent EULAR definition of “erosive disease”, on the 310 patients comprising the …

Objective To identify, in conservatively treated, very early arthritis patients, predictors of ≥1
erosion(s) at 2 years, and to construct a prediction model. Methods Community‐based adults …

Objective. Bone demineralization observed in early rheumatoid arthritis is not easily
measured. To measure bone loss and to discriminate between rheumatoid arthritis and other …