Fewer than half of patients with systemic sclerosis demonstrate modified Rodnan skin score
improvement during mycophenolate mofetil (MMF) treatment. To understand the molecular …

Objective. Forced vital capacity (FVC) and DLCO are used for screening of systemic
sclerosis–associated interstitial lung disease (SSc-ILD). The study purpose was to determine the …

Purpose: To evaluate the utility of cardiac magnetic resonance T1 mapping in early systemic
sclerosis and its association with skin score. Methods: In total, 24 consecutive patients with …

Objective Adipose tissues secrete adipokines, peptides with potent effects modulating
fibrosis, inflammation, and vascular homeostasis. Dysregulated adipose tissue biology and …

Background Esophageal dysfunction and gastro‐esophageal reflux disease ( GERD ) are
common among patients with systemic sclerosis ( SS c). Although high‐dose proton pump …

Objective To identify clinical factors, including esophageal dilation on chest high-resolution
computed tomography (HRCT), that are associated with pulmonary function decline in …

Background Skin fibrosis is the clinical hallmark of systemic sclerosis (SSc), where collagen
deposition and remodeling of the dermis occur over time. The most widely used outcome …

Patients with systemic sclerosis often seek information regarding complementary and
nutrition-based therapy. Some study results have shown that vitamins D and E, probiotics, turmeric, …

Introduction: Previously, we discovered similar esophageal gene expression patterns in
patients with systemic sclerosis and eosinophilic esophagitis where eosinophil/mast cell–…

Interstitial lung disease is the leading cause of death in systemic sclerosis (SSc)[1]. Despite
this, many transplant programs exclude SSc patients from transplantation consideration due …