Background: In a substantial proportion of patients with crescentic glomerulonephritis (CGN),
both anti-glomerular basement membrane (GBM) antibodies and antineutrophil …

Giant cell arteritis ( GCA ) is an autoimmune vasculitis affecting large and medium‐sized
arteries. Ample evidence indicates that GCA is a heterogeneous disease in terms of symptoms, …

Anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides (AAV) are systemic
autoimmune diseases characterized by necrotizing inflammation of small- to medium-sized …

Background A novel autoinflammatory syndrome was recently described in male patients
who harbored somatic mutations in the X-chromosomal UBA1 gene. These patients were …

Background Disease-specific studies have reported impaired humoral responses after
SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders treated with …

Objective Several lines of evidence indicate that B cells may be involved in the
immunopathology of giant cell arteritis (GCA) and polymyalgia rheumatica (PMR). This study was …

Giant cell arteritis (GCA) is the most frequent form of vasculitis in persons older than 50
years. Cranial and systemic large vessels can be involved.[18 F] fluorodeoxyglucose (FDG) …

Objective. To compare multiple serum markers for their ability to detect active disease in
patients with GCA and in those with PMR. Methods. Twenty-six markers related to immune cells …

Background Concerns have been raised regarding the risks of SARS-CoV-2 breakthrough
infections in vaccinated patients with immune-mediated inflammatory diseases treated with …

Purpose To analyze the data of the national registry of all Dutch primary immune deficiency (PID)
patients, according to the European Society for Immunodeficiencies (ESID) definitions. …