User profiles for ARMAND BENSUSSAN
 | Bensussan ArmandINSERM Verified email at inserm.fr Cited by 19998 |
Cutting edge: soluble HLA-G1 triggers CD95/CD95 ligand-mediated apoptosis in activated CD8+ cells by interacting with CD8
…, F Lenfant, A Alam, A Toubert, A Bensussan… - The journal of …, 2000 - journals.aai.org
The nonpolymorphic soluble HLA-G1 (sHLA-G1) isoform has been reported to be secreted
by trophoblast cells at the materno-fetal interface, suggesting that it may act as …
by trophoblast cells at the materno-fetal interface, suggesting that it may act as …
Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells
A Nassif, A Bensussan, L Boumsell, A Deniaud… - Journal of allergy and …, 2004 - Elsevier
BACKGROUND: Toxic epidermal necrolysis (TEN) is a very rare but extremely severe drug
reaction characterized by widespread apoptosis of epidermis with extensive blisters. We …
reaction characterized by widespread apoptosis of epidermis with extensive blisters. We …
[HTML][HTML] Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis
A Nassif, A Bensussan, N Bachot, M Bagot… - Journal of Investigative …, 2002 - Elsevier
Toxic epidermal necrolysis is an extremely severe drug reaction, manifesting itself by
widespread apoptosis of keratinocytes, generally considered to result from Fas/CD95–FasLigand …
widespread apoptosis of keratinocytes, generally considered to result from Fas/CD95–FasLigand …
[PDF][PDF] Blocking antibodies targeting the CD39/CD73 immunosuppressive pathway unleash immune responses in combination cancer therapies
…, N Gourdin, B Amigues, A Roussel, A Bensussan… - Cell reports, 2019 - cell.com
Immune checkpoint inhibitors have revolutionized cancer treatment. However, many cancers
are resistant to ICIs, and the targeting of additional inhibitory signals is crucial for limiting …
are resistant to ICIs, and the targeting of additional inhibitory signals is crucial for limiting …
IL‐10 produced by activated human B cells regulates CD4+ T‐cell activation in vitro
…, A Saussine, M Bagot, A Bensussan… - European journal of …, 2010 - Wiley Online Library
IL‐10‐producing regulatory B cells have been identified in mice and shown to downregulate
inflammation, making them potentially important for maintenance of tolerance. In this study, …
inflammation, making them potentially important for maintenance of tolerance. In this study, …
Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation.
…, AA Cardoso, A Bensussan… - Proceedings of the …, 1996 - National Acad Sciences
Herein we describe the molecular characterization of the human leukocyte activation antigen
CD100 and identify it as the first semaphorin, to our knowledge, in the immune system. …
CD100 and identify it as the first semaphorin, to our knowledge, in the immune system. …
[HTML][HTML] Evaluation of the potential role of cytokines in toxic epidermal necrolysis
…, L Lyonnet, L Michel, L Boumsell, A Bensussan… - Journal of Investigative …, 2004 - Elsevier
Toxic epidermal necrolysis is a rare disease observed as a consequence of adverse reactions
to drugs. It results in the widespread apoptosis of epidermal cells and has a high mortality …
to drugs. It results in the widespread apoptosis of epidermal cells and has a high mortality …
Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells
…, M Aguerre-Girr, S Fournel, F Malecaze, A Bensussan… - Blood, 2006 - ashpublications.org
HLA-G is a major histocompatibility complex class Ib molecule whose constitutive tissue
distribution is restricted mainly to trophoblast cells at the maternal-fetal interface during …
distribution is restricted mainly to trophoblast cells at the maternal-fetal interface during …
Inhibition of CD39 enzymatic function at the surface of tumor cells alleviates their immunosuppressive activity
…, N Bec, C Larroque, G Alberici, A Bensussan… - Cancer immunology …, 2015 - AACR
The ectonucleotidases CD39 and CD73 hydrolyze extracellular adenosine triphosphate (ATP)
and adenosine diphosphate (ADP) to generate adenosine, which binds to adenosine …
and adenosine diphosphate (ADP) to generate adenosine, which binds to adenosine …
IFNα kinoid vaccine-induced neutralizing antibodies prevent clinical manifestations in a lupus flare murine model
…, D Emilie, G Peltre, A Bensussan… - Proceedings of the …, 2009 - National Acad Sciences
A major involvement of IFNα in the etiopathogenesis of systemic lupus erythematosus has
been suggested by clinical observations, including the increase of serum levels of this …
been suggested by clinical observations, including the increase of serum levels of this …