Background: Cancer cachexia is a multifactorial syndrome that is poorly defined. Objective:
Our objective was to evaluate whether a 3-factor profile incorporating weight loss (≥10%), …

The adult mammalian central nervous system (CNS) contains a population of neural stem
cells (NSCs) 1 , 2 , 3 , 4 with properties said to include the generation of non-neural progeny 5 …

Malnutrition is not a new or a rare problem. In studies involving more than 1,327 hospitalized
adult patients, 40% to 55% were found to be either malnourished or at risk for malnutrition, …

The hypothesis that the last step in the biosynthesis of 4,7,10,13,16,19-22:6 from linolenate
is catalyzed by an acyl-CoA-dependent 4-desaturase has never been evaluated by direct …

The principle of treating-to-target has been successfully applied to many diseases outside
rheumatology and more recently to rheumatoid arthritis. Identifying appropriate therapeutic …

Vaccines play a critical role in combating the COVID-19 pandemic. Future control of the
pandemic requires improved vaccines with high efficacy against newly emerging SARS-CoV-2 …

… Stacy Bender, Abby Cook, Maree Ferguson, and Anne Voss are employees of Ross Products
Division. Susan Horn, Siobhan Sharkey, Randall Smout, Nancy Bergstrom, and George …

Objectives Treat-to-target recommendations have identified ‘remission’ as a target in systemic
lupus erythematosus (SLE), but recognise that there is no universally accepted definition …

The 90 kDa heat-shock proteins (HSP90s) play important roles during stress situations as
general chaperones and under physiological conditions in the conformational activation of …

Ets-related gene (ERG), which encodes a member of the Ets family of transcription factors,
is a potent oncogene. Chromosomal rearrangements involving ERG are found in acute …