Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and
internal organs that leads to profound disability and premature death. To identify new SSc …

Objectives To identify overall disease course, progression patterns and risk factors
predictive for progressive interstitial lung disease (ILD) in patients with systemic sclerosis-associated …

The aim of this study was to determine, through a genome-wide association study (GWAS),
the genetic components contributing to different clinical sub-phenotypes of systemic sclerosis …

Background Systemic sclerosis-associated interstitial lung disease (ILD) carries a high
mortality risk; expert guidance is required to aid early recognition and treatment. We aimed to …

Background In the Safety and Efficacy of Nintedanib in Systemic Sclerosis (SENSCIS) trial,
nintedanib reduced the rate of decline in forced vital capacity (FVC) in patients with systemic …

Interstitial lung diseases (ILDs), which can arise from a broad spectrum of distinct aetiologies,
can manifest as a pulmonary complication of an underlying autoimmune and connective …

Objective To compare the clinical, functional, and radiographic outcomes in patients with
enthesitis‐related arthritis (ERA) with those in patients with other subtypes of juvenile idiopathic …

Objective To assess the safety and efficacy of rituximab in systemic sclerosis (SSc) in clinical
practice. Methods We performed a prospective study including patients with SSc from the …

Systemic sclerosis (SSc) is a systemic autoimmune disease affecting multiple organ systems,
including the lungs. Interstitial lung disease (ILD) is the leading cause of death in SSc. …

Rationale: Interstitial lung disease (ILD) represents a major challenge in systemic sclerosis (SSc),
but there are no precise, population-based data on its overall impact, limiting …