Background: Several members of the GIMAP gene family have been suggested as being
involved in different aspects of the immune system in different species. Recently, a mutation in …

Please cite this paper as: Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms
are associated with discoid and subacute cutaneous lupus erythematosus. Experimental …

Objective. Several candidate genes have been implicated in susceptibility for systemic
lupus erythematosus (SLE), a complex autoimmune disease. The proposed genes include …

Objective. A large number of genes, including several not previously implicated in SLE
susceptibility, have recently been identified or confirmed by genome-wide association studies (…

Background Human polymorphisms affecting gut epithelial barrier and interactions with
bacteria predispose to the inflammatory bowel diseases (IBD) Crohn's disease (CD) and …

Background Lupus erythematosus (LE) is a heterogeneous disease ranging from mainly
skin-restricted manifestations (discoid LE [DLE] and subacute cutaneous LE) to a progressive …

Background neuropeptide S (NPS) and its receptor NPSR1 act along the hypothalamic-pituitary-adrenal
axis to modulate anxiety, fear responses, nociception and inflammation. The …

Breast milk contains several components that provide specific immunity and affect the maturation
of the infant's immune system. The aim of this study was to analyze the effects of breast …

Clinical genetic testing is recommended for individuals diagnosed with autism spectrum
disorder. There are only a few reports of how these recommendations are followed and …

Objectives To investigate whether 10 single nucleotide polymorphisms (SNPs) and haplotypes
in the STAT4 gene, previously associated with systemic lupus erythematosus (SLE) in a …