Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial
Background Myocardial injury after non-cardiac surgery (MINS) increases the risk of
cardiovascular events and deaths, which anticoagulation therapy could prevent. Dabigatran …
cardiovascular events and deaths, which anticoagulation therapy could prevent. Dabigatran …
Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing
Background Alopecia areata (AA) is a common T cell–mediated disorder with limited
therapeutics. A molecular profile of cytokine pathways in AA tissues is lacking. Although studies …
therapeutics. A molecular profile of cytokine pathways in AA tissues is lacking. Although studies …
[HTML][HTML] Adjunct immune globulin for vaccine-induced immune thrombotic thrombocytopenia
…, JM Shrum, ZAA Al Maqrashi, A Shroff… - … England Journal of …, 2021 - Mass Medical Soc
The use of high-dose intravenous immune globulin (IVIG) plus anticoagulation is recommended
for the treatment of vaccine-induced immune thrombotic thrombocytopenia (VITT), a rare …
for the treatment of vaccine-induced immune thrombotic thrombocytopenia (VITT), a rare …
Extensive alopecia areata is reversed by IL-12/IL-23p40 cytokine antagonism
To the Editor: Alopecia areata (AA) is a prevalent (approximately 1.7% lifetime risk) disease.
1 Although it has a large effect on patients’ quality of life and poses a large economic burden…
1 Although it has a large effect on patients’ quality of life and poses a large economic burden…
Improving the quality of colonoscopy bowel preparation using an educational video
…, S Verma, J McGowan, BE Smith, A Shroff… - Canadian Journal of …, 2013 - hindawi.com
Colonoscopy is the preferred modality for colon cancer screening. A successful colonoscopy
requires proper bowel preparation. Adequate bowel preparation continues to remain a …
requires proper bowel preparation. Adequate bowel preparation continues to remain a …
[HTML][HTML] Oxidative stress and skin fibrosis
A Shroff, A Mamalis, J Jagdeo - Current pathobiology reports, 2014 - Springer
Fibrosis is defined as increased fibroblast proliferation and deposition of extracellular matrix
components with potential clinical ramifications including organ dysfunction and failure. …
components with potential clinical ramifications including organ dysfunction and failure. …
Impact of the combination of daptomycin and trimethoprim-sulfamethoxazole on clinical outcomes in methicillin-resistant Staphylococcus aureus infections
…, RP Mynatt, L Avery, A Shroff… - Antimicrobial Agents …, 2015 - Am Soc Microbiol
Complicated Staphylococcus aureus infections, including bacteremia, are often associated
with treatment failures, prolonged hospital stays, and the emergence of resistance to primary …
with treatment failures, prolonged hospital stays, and the emergence of resistance to primary …
[HTML][HTML] Successful use of ustekinumab therapy in refractory severe atopic dermatitis
A Shroff, E Guttman-Yassky - JAAD case reports, 2015 - Elsevier
Discussion Ustekinumab is a human monoclonal antibody targeting the p40 subunit of
interleukin (IL)-12/23, effectively blocking the IL-23/T helper cell 17 (Th17) pathway, 3 and is …
interleukin (IL)-12/23, effectively blocking the IL-23/T helper cell 17 (Th17) pathway, 3 and is …
Use of 308 nm excimer laser for the treatment of chronic hand and foot eczema
A Shroff, D Malajian, T Czarnowicki… - International journal …, 2016 - Wiley Online Library
Background Chronic hand and foot eczema ( CHFE ), a prevalent debilitating disorder
affecting approximately 15% of the population, presents a socioeconomic and psychosocial …
affecting approximately 15% of the population, presents a socioeconomic and psychosocial …
[HTML][HTML] A case of pyoderma gangrenosum misdiagnosed as necrotizing infection: a potential diagnostic catastrophe
MG Saffie, A Shroff - Case Reports in Infectious Diseases, 2018 - hindawi.com
In this article, we present a case of pyoderma gangrenosum (PG), misdiagnosed initially as
a necrotizing infection that significantly worsened due to repeated surgical debridement and …
a necrotizing infection that significantly worsened due to repeated surgical debridement and …