Staphylococcus aureus: staphylokinase

MI Bokarewa, T Jin, A Tarkowski - … journal of biochemistry & cell biology, 2006 - Elsevier
Staphylokinase is a 136 aa long bacteriophage encoded protein expressed by lysogenic
strains of Staphylococcus aureus. Present understanding of the role of staphylokinase during …

Catecholaminergic suppression of immunocompetent cells

J Bergquist, A Tarkowski, A Ewing, R Ekman - Immunology today, 1998 - cell.com
The synthesis of catecholamines by immunocompetent cells has now been demonstrated.
In addition, catecholamines have been discovered inside the nuclear membrane and may …

Resistin, an adipokine with potent proinflammatory properties

…, L Dahlberg, U Smith, A Tarkowski - The Journal of …, 2005 - journals.aai.org
The adipokine resistin is suggested to be an important link between obesity and insulin
resistance. In the present study, we assessed the impact of resistin as inflammatogenic cytokine …

A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells

…, H Nygren, Ö Ouchterlony, A Tarkowski - Journal of …, 1983 - Elsevier
A solid-phase enzyme-linked immunosorbent assay (ELISPOT) is described for enumeration
of cells secreting specific antibody. Spleen cells from immunized mice are incubated in …

Infectious arthritis

A Tarkowski - Best practice & research Clinical rheumatology, 2006 - Elsevier
In contrast to the outstanding achievements made in therapy for autoimmune arthritides, not
least rheumatoid arthritis, the pace of progress in therapy for infectious arthritis remains slow…

Staphylococcus aureus Resistance to Human Defensins and Evasion of Neutrophil Killing via the Novel Virulence Factor Mprf Is Based on Modification of Membrane Lipids with …

…, WF Nieuwenhuizen, G Jung, A Tarkowski… - The Journal of …, 2001 - rupress.org
Defensins, antimicrobial peptides of the innate immune system, protect human mucosal
epithelia and skin against microbial infections and are produced in large amounts by neutrophils…

Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses

…, E Holme, IM Jonsson, A Tarkowski - Journal of Leucocyte …, 2004 - academic.oup.com
We report that mitochondrial DNA (mtDNA) is inflammatogenic in vitro and in vivo as a result
of the presence of unmethylated CpG sequences and its oxidative status. Purified human …

Staphylococcus aureus resists human defensins by production of staphylokinase, a novel bacterial evasion mechanism

…, T Foster, J Mitchell, J Higgins, A Tarkowski - The journal of …, 2004 - journals.aai.org
α-Defensins are peptides secreted by polymorphonuclear cells and provide antimicrobial
protection mediated by disruption of the integrity of bacterial cell walls. Staphylokinase is an …

Discovery of endogenous catecholamines in lymphocytes and evidence for catecholamine regulation of lymphocyte function via an autocrine loop.

J Bergquist, A Tarkowski, R Ekman… - Proceedings of the …, 1994 - National Acad Sciences
Evidence has been obtained that catecholamines and their metabolites are present in single
lymphocytes and extracts of T- and B-cell clones by use of capillary electrophoresis with …

Increased intrathecal levels of the angiogenic factors VEGF and TGF-β in Alzheimer's disease and vascular dementia

E Tarkowski, R Issa, M Sjögren, A Wallin… - Neurobiology of …, 2002 - Elsevier
The aim of the present study was to investigate, in patients with Alzheimer’s disease (AD),
and vascular dementia (VAD), patterns of local release of vascular endothelial growth factor (…