OBJECTIVE--To investigate whether semen quality has changed during the past 50 years.
DESIGN--Review of publications on semen quality in men without a history of infertility …

Male reproductive health has deteriorated in many countries during the last few decades. In
the 1990s, declining semen quality has been reported from Belgium, Denmark, France, and …

Standard sperm parameters have a limited power for prediction of the chance of natural
conception. Recent studies have indicated that the sperm chromatin structure assay (SCSA) …

Background The association between aging-related testosterone deficiency and late-onset
hypogonadism in men remains a controversial concept. We sought evidence-based criteria …

CONTEXT: New data regarding the diagnosis and treatment of male infertility have emerged
and led to an update of the European Association of Urology (EAU) guidelines for Male …

Context: The cause of declining testosterone (T) in aging men and their relationships with
risk factors are unclear. Objective: The objective of the study was to investigate the …

BACKGROUND: The sperm chromatin structure assay (SCSA) has been suggested as a
predictor of fertility in vivo as well as in vitro. The available data however, have been based on …

Background Semen analysis is part of the routine assessment of infertile couples. WHO
defines a sperm concentration above 20×10 6 per mL seminal fluid as normal. We studied the …

INTRODUCTION: Sperm chromatin integrity assessment has been suggested as a fertility
predictor. The aim of this study was to examine the relationship between the results of sperm …

Context: The diagnosis of late-onset hypogonadism (LOH) in older men with age-related
declines in testosterone (T) is currently not well characterized. Objective: Our objective was to …