… Alan J. Silman… Silman had full access to all of the data in the study and takes
responsibility for the integrity of the data and the accuracy of the data analysis. …

Objective Twin concordance data for rheumatoid arthritis (RA) on their own provide only
limited insight into the relative genetic and environmental contribution to the disease. We …

Background The association between aging-related testosterone deficiency and late-onset
hypogonadism in men remains a controversial concept. We sought evidence-based criteria …

Chapter summary The prevalence of rheumatoid arthritis (RA) is relatively constant in many
populations, at 0.5–1.0%. However, a high prevalence of RA has been reported in the Pima …

The relationship between use of corticosteroids and fracture risk was estimated in a meta‐analysis
of data from seven cohort studies of ∼42,000 men and women. Current and past use …

Context: The cause of declining testosterone (T) in aging men and their relationships with
risk factors are unclear. Objective: The objective of the study was to investigate the …

Objectives: To investigate the claim that 90% of episodes of low back pain that present to
general practice have resolved within one month. Design: Prospective study of all adults …

The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility
to more common diseases than any other region of the human genome, including almost …

Objectives: To quantify the relative contribution of premorbid and episode specific factors in
determining the long term persistence of disabling symptoms of low back pain. Design:…

OBJECTIVES To systematically evaluate the available evidence on occupational risk factors
of shoulder pain. METHODS Relevant reports were identified by a systematic search of …