Impaired clearance of dying cells in systemic lupus erythematosus

US Gaipl, RE Voll, A Sheriff, S Franz, JR Kalden… - Autoimmunity …, 2005 - Elsevier
Impaired clearance of apoptotic cell material has been implicated in the pathogenesis of
systemic lupus erythematosus (SLE). Besides many other molecules, C1q and DNaseI …

[HTML][HTML] C-reactive protein triggers cell death in ischemic cells

A Sheriff, S Kayser, P Brunner, B Vogt - Frontiers in Immunology, 2021 - frontiersin.org
C-reactive protein (CRP) is the best-known acute phase protein. In humans, almost every
type of inflammation is accompanied by an increase of CRP concentration. Until recently, the …

Attraction of phagocytes by apoptotic cells is mediated by lysophosphatidylcholine

RB Mueller, A Sheriff, US Gaipl, S Wesselborg… - …, 2007 - Taylor & Francis
Apoptotic cells promote the phagocytosis of themselves via the exposure of “eat me” signals.
Furthermore, a second, “find me” signal is required to attract phagocytes. In this review the …

[HTML][HTML] Complement activation in kidneys of patients with COVID-19

…, HM Jäck, K Überla, G Lochnit, A Sheriff… - Frontiers in …, 2021 - frontiersin.org
Most patients who became critically ill following infection with COVID-19 develop severe acute
respiratory syndrome (SARS) attributed to a maladaptive or inadequate immune response…

[PDF][PDF] C-reactive protein levels predict systolic heart failure and outcome in patients with first ST-elevation myocardial infarction treated with coronary angioplasty

C Stumpf, A Sheriff, S Zimmermann… - Archives of medical …, 2017 - termedia.pl
Results: C-reactive protein levels reached a peak after 48 h. Patients with STEMI and signs
of HF showed significantly higher peak CRP levels. We found a positive correlation between …

[HTML][HTML] C-reactive protein apheresis as anti-inflammatory therapy in acute myocardial infarction: results of the CAMI-1 study

…, P Nordbeck, C Butter, H Skarabis, A Sheriff… - Frontiers in …, 2021 - frontiersin.org
Background: C-reactive protein (CRP) is a well-known marker of inflammation. It is less
known that CRP mediates tissue damage in acute myocardial infarction (AMI) thus potentially …

Selective apheresis of C‐reactive protein: A new therapeutic option in myocardial infarction?

A Sheriff, R Schindler, B Vogt… - Journal of clinical …, 2015 - Wiley Online Library
Ahmed Sheriff and Ralf Schindler contributed equally to this … Ahmed Sheriff and Ralf
Schindler contributed equally to this … Ahmed Sheriff and Ralf Schindler contributed equally to this …

Radiosynthesis, in vitro validation, and in vivo evaluation of 18F-labeled COX-1 and COX-2 inhibitors

TJ McCarthy, AU Sheriff, MJ Graneto… - Journal of Nuclear …, 2002 - Soc Nuclear Med
In this article, we describe the radiosynthesis and evaluation of 18 F-labeled cyclooxygenase
(COX) inhibitors. F-SC63217 is selective to COX-1 and has a COX-1 inhibitory …

Selective C‐reactive protein‐apheresis in patients

W Ries, F Heigl, C Garlichs, A Sheriff… - Therapeutic …, 2019 - Wiley Online Library
C‐reactive protein (CRP), the prototype human acute‐phase protein, is a well‐known
marker of inflammation. However, CRP may also mediate tissue damage in various human …

[HTML][HTML] First-in-man: case report of selective C-reactive protein apheresis in a patient with SARS-CoV-2 infection

…, R Hettich, C Bock, S Kayser, A Sheriff - The American journal …, 2020 - ncbi.nlm.nih.gov
Objective: Unusual clinical course Background: C-reactive protein (CRP) plasma levels in
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel viral disease, are …