The purpose of this review is to guide clinicians and researchers who wish to use quality of life (QOL) measures in dermatology. Definitions of key words are given, with a guide to descriptions of the adverse effects of skin disease. The reasons for measuring QOL in dermatology are explained, with descriptions of the use of disease specific, dermatology specific, general health and utility measure questionnaires. Measurement methods of QOL in children and the family impact of skin disease are also described. There is advice about how to choose which method to use, and where to find the questionnaires.