Interleukin-6 and a delay of neutrophil apoptosis after major surgery

E Kobayashi; H Yamauchi

doi:10.1001/archsurg.1997.01430260107023

Interleukin-6 and a delay of neutrophil apoptosis after major surgery

Arch Surg. 1997 Feb;132(2):209-10. doi: 10.1001/archsurg.1997.01430260107023.

Authors

E Kobayashi¹, H Yamauchi

Affiliation

¹ Department of Clinical Pharmacology, Jichi Medical School, Tochigi, Japan.

PMID: 9041929
DOI: 10.1001/archsurg.1997.01430260107023

Abstract

Surgical treatments affect host immune systems. Apoptosis of the circulatory lymphocytes and an elevation of the number of neutrophils are induced by surgery. These alterations are not dependent only on the stress hormone. The course of neutrophilia and the serum concentration of interleukin-6 are given after various surgical treatments. Neutrophil-mediated lung injury is discussed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Apoptosis*
Humans
Interleukin-6 / blood*
Neutrophils*
Stress, Physiological / blood*
Surgical Procedures, Operative*
Time Factors

Substances

Interleukin-6