Bilateral optic neuropathy associated with the crest variant of scleroderma

Eur J Ophthalmol. 1993 Oct-Dec;3(4):219-22. doi: 10.1177/112067219300300408.

Abstract

We report a case of bilateral optic neuropathy associated with the CREST syndrome, a variant of scleroderma. Immunosuppressive therapy achieved significant improvement of the visual symptoms for two years. The pathophysiological mechanisms underlying this unique association remain unclear.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Azathioprine / therapeutic use
  • CREST Syndrome / complications*
  • CREST Syndrome / drug therapy
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Methylprednisolone / therapeutic use
  • Optic Nerve Diseases / drug therapy
  • Optic Nerve Diseases / etiology*
  • Visual Acuity
  • Visual Fields

Substances

  • Azathioprine
  • Methylprednisolone