Pleuro-pulmonary manifestations of systemic lupus erythematosus: clinical features of its subgroups. Prognostic and therapeutic implications

Chest. 1985 Jul;88(1):129-35. doi: 10.1378/chest.88.1.129.

Abstract

Correct identification of the subsets of pulmonary lupus has an unquestioned importance in planning the proper therapeutic regimen in this extremely variegated disease. Asymptomatic pulmonary lupus needs no treatment; however, pulmonary involvement in lupus may be life threatening, in which case prompt and aggressive treatment is mandatory. The different aspects of pulmonary lupus are demonstrated through the clinical histories of patients who suffered from pleuro-pulmonary lupus. The following entities are presented: lupus pneumonitis, lymphocytic interstitial pneumonia, pulmonary hypertension, pulmonary hemorrhage, pulmonary embolism associated with circulating lupus anticoagulant, lupus pleuritis and weakness of the diaphragm.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Blood Coagulation Factors / antagonists & inhibitors
  • Blood Coagulation Factors / metabolism
  • Diaphragm
  • Female
  • Humans
  • Hypertension, Pulmonary / complications
  • Lung Diseases / complications*
  • Lupus Coagulation Inhibitor
  • Lupus Erythematosus, Systemic / classification
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / metabolism
  • Middle Aged
  • Muscular Diseases / complications
  • Pleural Diseases / complications*
  • Pleurisy / complications
  • Pulmonary Embolism / complications
  • Pulmonary Fibrosis / complications
  • Radiography, Thoracic

Substances

  • Blood Coagulation Factors
  • Lupus Coagulation Inhibitor