Scleroderma Renal Crisis

Loïc Guillevin; Luc Mouthon

doi:10.1016/j.rdc.2015.04.008

Scleroderma Renal Crisis

Rheum Dis Clin North Am. 2015 Aug;41(3):475-88. doi: 10.1016/j.rdc.2015.04.008. Epub 2015 May 26.

Authors

Loïc Guillevin¹, Luc Mouthon²

Affiliations

¹ Department of Internal Medicine, Centre de Référence Maladies Systémiques et Auto-Immunes Rares, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Université Paris Descartes, Paris, France. Electronic address: loic.guillevin@cch.aphp.fr.
² Department of Internal Medicine, Centre de Référence Maladies Systémiques et Auto-Immunes Rares, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Université Paris Descartes, Paris, France.

PMID: 26210130
DOI: 10.1016/j.rdc.2015.04.008

Abstract

Scleroderma renal crisis is a rare complication of systemic sclerosis (SSc) that remains severe. Prompt recognition and initiation of therapy with an angiotensin-converting-enzyme inhibitor offer the best chance to achieve a good outcome. SSc prevalence is poorly known, with disparities among countries.

Keywords: Acute renal failure; Angiotensin-converting-enzyme inhibitors; Arterial hypertension; Scleroderma renal crisis; Systemic sclerosis.

Publication types

Review

MeSH terms

Angiotensin-Converting Enzyme Inhibitors / therapeutic use
Female
Humans
Male
Middle Aged
Pregnancy
Pregnancy Complications
Renal Insufficiency / etiology*
Renal Insufficiency / therapy
Scleroderma, Systemic / complications*
Scleroderma, Systemic / pathology

Substances

Angiotensin-Converting Enzyme Inhibitors