Syndromes of thrombotic microangiopathy

James N George; Carla M Nester

doi:10.1056/NEJMra1312353

Syndromes of thrombotic microangiopathy

N Engl J Med. 2014 Aug 14;371(7):654-66. doi: 10.1056/NEJMra1312353.

Authors

James N George¹, Carla M Nester

Affiliation

¹ From the Department of Biostatistics and Epidemiology, College of Public Health, and the Department of Internal Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City (J.N.G.); and the Stead Family Department of Pediatrics and Department of Internal Medicine, University of Iowa, Iowa City (C.M.N.).

PMID: 25119611
DOI: 10.1056/NEJMra1312353

Abstract

This review article covers the diverse pathophysiological pathways that can lead to microangiopathic hemolytic anemia and a procoagulant state with or without damage to the kidneys and other organs.

Publication types

Review

MeSH terms

Humans
Purpura, Thrombotic Thrombocytopenic / diagnosis
Purpura, Thrombotic Thrombocytopenic / therapy
Thrombotic Microangiopathies* / diagnosis
Thrombotic Microangiopathies* / etiology
Thrombotic Microangiopathies* / therapy