Objective: The relationship between depression and physical disability in multiple sclerosis (MS) is unclear. This investigation examines the interaction between disability and perfectionism in predicting depression in MS.
Methods: Participants (n=51) completed the frost multidimensional perfectionism scale (FMPS), the Chicago multiscale depression inventory (CMDI), and the Expanded Disability Status Scale (EDSS).
Results: Regression revealed that the FMPS×EDSS interaction predicted depression above the variance predicted by each variable alone. Perfectionism predicted depression at high levels of disability.
Conclusion: Our results suggest a means of reconciling inconsistent findings regarding physical disability and depression in MS and offer a potential target for psychotherapy.
Keywords: Depression; Multiple sclerosis; Neuropsychology; Physical disability.
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