Abstract
The Hopkins lupus cohort is a longitudinal cohort study of over 2,000 systemic lupus erythematosus (SLE) patients, who are seen quarterly. This review covers ten important clinically-relevant studies of the cohort. These studies include the function of prednisone in atherosclerosis and thrombosis, the preventive function of hydroxychloroquine, new insights into rare neurological manifestations, and treatment of flares with bursts of steroids rather than maintenance steroids.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Antirheumatic Agents / therapeutic use
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Cardiovascular Diseases / etiology
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Cognition Disorders / etiology
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Cohort Studies
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Creatinine / urine
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Glucocorticoids / adverse effects
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Glucocorticoids / therapeutic use
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Humans
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Hydroxychloroquine / therapeutic use
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Longitudinal Studies
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Lupus Coagulation Inhibitor / blood
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Lupus Erythematosus, Systemic / complications
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Lupus Erythematosus, Systemic / drug therapy*
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Lupus Erythematosus, Systemic / immunology
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Lupus Nephritis / diagnosis
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Lupus Nephritis / drug therapy
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Myelitis / etiology
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Prednisone / adverse effects
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Prednisone / therapeutic use
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Proteinuria / etiology
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Vitamin D Deficiency / complications
Substances
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Antirheumatic Agents
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Glucocorticoids
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Lupus Coagulation Inhibitor
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Hydroxychloroquine
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Creatinine
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Prednisone