Psoriasis uncovered--measuring burden of disease impact in a survey of Australians with psoriasis

Australas J Dermatol. 2013 Feb:54 Suppl 1:1-6. doi: 10.1111/ajd.12010.

Abstract

Background/objectives: Internationally, the understanding of psoriasis has advanced in recent years to the point now where it is no longer considered a benign or cosmetic skin condition but a systemic, immune-mediated disease associated with significant comorbidities and considerable detriment to quality of life. The aim of this study was to gain a better understanding of the physical, psychosocial and medical burden of psoriasis on Australian adults and the impact on health status.

Methods: Two large-scale multi-centre cross-sectional studies of Australian adults with psoriasis were conducted during 2010 and 2011, with the participation of a national patient representative group (Psoriasis Australia). The studies were based on detailed questionnaires that were self-completed by individuals with psoriasis.

Results: A total of 362 and 330 completed surveys were received in 2010 and 2011, respectively. A significant physical, psychosocial and medical burden was reported by the respondents. It was noteworthy that patients reported actively concealing their disease from the general public (83%), work colleagues (65%), friends (58%), employers (49%), family (40%), close friends (39%) and spouse/partner (20%). The mean five-dimension European quality of life (EQ-5D) score for the 2011 cohort was 0.73, representing a significant impact on their HRQoL. The presence of comorbidities, found in three-quarters of the cohort, was associated with an even greater detriment to their HRQoL (mean score 0.64).

Conclusions: Psoriasis imposes a significant psychosocial burden on the lives of patients, including a profound impact upon their personal and professional relationships, social interactions and quality of life, to a degree comparable to other serious chronic conditions. This study highlights the importance of collaboration between primary and specialist health-care providers in developing patient management strategies that address the spectrum of physical and psychological manifestations associated with psoriasis.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Cutaneous
  • Adolescent
  • Adult
  • Aged
  • Australia
  • Cohort Studies
  • Cross-Sectional Studies
  • Dermatologic Agents / administration & dosage
  • Early Diagnosis
  • Female
  • Health Status
  • Humans
  • Male
  • Middle Aged
  • Psoriasis / diagnosis
  • Psoriasis / drug therapy
  • Psoriasis / psychology*
  • Quality of Life*
  • Risk Factors
  • Severity of Illness Index
  • Sickness Impact Profile
  • Surveys and Questionnaires

Substances

  • Dermatologic Agents