MRI in OA: from cartilage to bone marrow lesion

Osteoporos Int. 2012 Dec:23 Suppl 8:S867-9. doi: 10.1007/s00198-012-2166-8. Epub 2012 Nov 22.

Abstract

In contrast to radiography, magnetic resonance imaging permits visualization of all articular structures affected by osteoarthritis. Many studies have demonstrated its potential to elucidate the pathophysiological phenomena that lead to joint destruction, quantify cartilage damage, and establish risk factors for chondrolysis. Bone marrow lesion is a well-recognized process localized just beneath the subchondral bone that is responsible for clinical symptoms and structural changes not only to bone but also to cartilage.

Publication types

  • Review

MeSH terms

  • Animals
  • Bone Density Conservation Agents / pharmacology
  • Bone Marrow / drug effects
  • Bone Marrow / pathology*
  • Bone Marrow Diseases / diagnosis
  • Bone Marrow Diseases / etiology
  • Cartilage, Articular / pathology*
  • Humans
  • Magnetic Resonance Imaging / methods
  • Osteoarthritis, Knee / complications
  • Osteoarthritis, Knee / diagnosis*

Substances

  • Bone Density Conservation Agents