Abstract
This is a discussion of acute gouty arthritis, seen for over 50 years of engagement. It addresses the evolution of our current understanding of the interaction between urate crystals and key cellular components of the gouty inflammatory paroxysm, with new material on pathogenesis.
Publication types
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Historical Article
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Arthritis, Gouty / etiology
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Arthritis, Gouty / history*
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Arthritis, Gouty / physiopathology
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Crystallization
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History, 20th Century
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History, 21st Century
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Humans
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In Vitro Techniques
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Inflammasomes / physiology
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Monocytes / physiology
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Neutrophils / physiology
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Research / history
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Uric Acid / chemistry