The authors analyzed data collected by the Registry of the Orthopedic Prosthetic Implantology in Italy. They found a higher rate of total hip arthroplasty on the right side (58%) in comparison with the left side in patients affected by primary coxarthrosis. To test whether laterality was the cause of this, they checked the prevalence of the upper and lower limbs in 262 patients treated for monolateral total hip prosthesis. They found that the percentage of left-handed patients was very low (0.8-6.5%). The percentage of left-footed patients was, instead, 26.5% for power tasks. They observed that, while the rate of arthroplasties on the right side was similar to that of the left side (50.7 and 49.3%) in the right-footed patients, there was a clear-cut prevalence in the number of operations on the right hip (76.8%) in comparison to the left one (23.2%) in the left-footed patients. The authors suggested that, in left-footed patients, the right side was subjected to greater stress.