Background and research objectives: :In recent years, health-related quality of life (HRQoL) has been increasingly used as an indicator of health outcome. The aims of the study were to compare the HRQoL of patients with coronary artery disease (CAD) to patients without CAD and also to determine the HRQoL of patients with CAD and the factors affecting their quality of life.
Subjects and methods: Patients with CAD who attend the outpatients' clinic in the Cardiology Department at Trakya University's Medicine Faculty Hospital agreed to be interviewed. One hundred patients with CAD and 100 people serving as patients without CAD were included in this cross-sectional study. Patients with CAD and patients without CAD were matched by age, sex, marital status, and income. Health-related quality of life was measured with the generic HRQoL instrument.
Results and conclusions: CAD patients' HRQoL scores differed significantly from patients without CAD. Compared to patients without CAD, the HRQoL of patients with CAD was lower in the dimensions of mobility (P < .001), hearing (P = .022), breathing (P < .001), elimination (P = .035), usual activities (P < .001), mental function (P = .004), discomfort and symptoms (P = .018), vitality (P = .006), sexual activity (P < .001), and total score (P < .001). Patients with CAD had lower HRQoL scores than patients without CAD. In patients with CAD, age and sex independently affected the HRQoL. Older patients and women had worse HRQoL. Coronary artery disease negatively affects HRQoL. It is thought that interventions to increase patients' quality of life may improve their HRQoL.