IgG4-positive pulmonary disease

J Thorac Imaging. 2007 Nov;22(4):360-2. doi: 10.1097/RTI.0b013e31813fab9f.

Abstract

We report herein high-resolution computed tomography findings from a patient with IgG4-related pulmonary disease for the first time. The 61-year-old male patient complained of low-grade fever, dry mouth, and night sweats. He was diagnosed as having autoimmune pancreatitis, Sjögren syndrome, and elevated serum IgG4. High-resolution computed tomography of the lungs showed dense alveolar consolidation and air bronchograms in bilateral perihilar regions. IgG4-positive lymphoplasmacytes were detected in pulmonary lesions by immunostaining of biopsy samples. IgG4-related pulmonary disease can be associated with various radiologic findings.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Diagnosis, Differential
  • Humans
  • Immunoglobulin G / blood*
  • Lung Diseases / blood
  • Lung Diseases / diagnostic imaging*
  • Lung Diseases / immunology
  • Male
  • Middle Aged
  • Pancreatitis / blood
  • Pancreatitis / diagnosis
  • Pancreatitis / immunology
  • Sjogren's Syndrome / blood
  • Sjogren's Syndrome / diagnosis
  • Sjogren's Syndrome / immunology
  • Tomography, X-Ray Computed

Substances

  • Immunoglobulin G