Severe temporomandibular dysfunction and joint destruction after intra-articular injection of triamcinolone

J Oral Pathol Med. 2005 Mar;34(3):184-6. doi: 10.1111/j.1600-0714.2004.00247.x.

Abstract

Background: Steroid injections into joints are frequently used to control symptomatic pain. Risks associated with intra-articular steroid injections are not well documented.

Methods: We report the case of a 29-year-old woman who was referred to a dental surgeon because of a suspected relationship between persisting chronic back pain and an arthrosis of the temporomandibular joint (TMJ).

Results: The dental surgeon diagnosed capsulitis of the right TMJ and injected 40 mg triamcinolone into the joint. Within 4 months the patient developed progressive pain and trismus of the right TMJ and the intra-articular injection was repeated. An occlusal splint slightly improved the patients' symptoms but induced crepitus. Magnetic resonance imaging revealed a disk dislocation in the right TMJ and severe necrosis of the condyle. The patient had persisting pain and ankylosis. Surgical restoration of the TMJ revealed a bony apposition in the fossa deformed with the socket of the joint, extensive medial erosion of the condyle and complete destruction of the disk.

Conclusion: This case report supports earlier observations that intra-articular glucocorticoid injections, if used in a wrong way, may cause severe destruction of a joint.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Ankylosis / chemically induced
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / adverse effects*
  • Cartilage, Articular / drug effects
  • Female
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / adverse effects*
  • Humans
  • Injections, Intra-Articular
  • Joint Dislocations / chemically induced
  • Mandibular Condyle / drug effects
  • Necrosis
  • Temporomandibular Joint Disc / drug effects
  • Temporomandibular Joint Disorders / chemically induced*
  • Triamcinolone / administration & dosage
  • Triamcinolone / adverse effects*
  • Trismus / chemically induced

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Triamcinolone