Crohn's-associated chronic recurrent multifocal osteomyelitis responsive to infliximab

Ellen Carpenter; Mary Anne Jackson; Craig A Friesen; Marc Scarbrough; Charles C Roberts

doi:10.1016/j.jpeds.2003.12.038

Crohn's-associated chronic recurrent multifocal osteomyelitis responsive to infliximab

J Pediatr. 2004 Apr;144(4):541-4. doi: 10.1016/j.jpeds.2003.12.038.

Authors

Ellen Carpenter¹, Mary Anne Jackson, Craig A Friesen, Marc Scarbrough, Charles C Roberts

Affiliation

¹ Inflammatory Bowel Disease Program, Section of Gastroenterology, The Children's Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA.

PMID: 15069408
DOI: 10.1016/j.jpeds.2003.12.038

Abstract

We report a case of chronic recurrent clavicular osteomyelitis in association with Crohn disease. Steroid therapy resulted in partial remission; however, intractable shoulder pain and an enlarging clavicular mass subsequently recurred. Infliximab therapy resulted in significant improvement in the degree of bone pain and resolution of the large sclerotic clavicular lesion.

Publication types

Case Reports

MeSH terms

Antibodies, Monoclonal / therapeutic use*
Child
Chronic Disease
Clavicle*
Crohn Disease / complications
Crohn Disease / drug therapy*
Female
Gastrointestinal Agents / therapeutic use*
Humans
Infliximab
Osteomyelitis / complications
Osteomyelitis / drug therapy*
Pain / drug therapy
Pain / etiology

Substances

Antibodies, Monoclonal
Gastrointestinal Agents
Infliximab