[Chloroquine cardiomyopathy revealed by complete atrio-ventricular block. A case report]

Arch Mal Coeur Vaiss. 2002 Sep;95(9):833-7.
[Article in French]

Abstract

We describe a rare case of chloroquine cardiomyopathy occurring during long term (7 years) treatment for rheumatoid polyarthritis in a 42 year old woman. There was an isolated acute severe conduction defect, which is particularly rare. Histological study with the electron microscope allowed confirmation of this diagnosis. We report here the secondary cardiological effects of this frequently used synthetic antimalarial.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acute Disease
  • Adult
  • Antirheumatic Agents / adverse effects*
  • Antirheumatic Agents / therapeutic use
  • Arthritis, Rheumatoid / drug therapy
  • Cardiomyopathies / chemically induced*
  • Cardiomyopathies / pathology
  • Chloroquine / adverse effects*
  • Chloroquine / therapeutic use
  • Female
  • Heart Block / chemically induced*
  • Heart Block / complications
  • Humans
  • Microscopy, Electron

Substances

  • Antirheumatic Agents
  • Chloroquine