Rapid and complete resolution of proteinuria due to renal amyloidosis in a patient with rheumatoid arthritis treated with infliximab

Arthritis Rheum. 2002 Oct;46(10):2571-3. doi: 10.1002/art.10581.

Abstract

We describe herein a patient with rheumatoid arthritis who developed proteinuria due to AA amyloidosis, in whom the inflammatory disease was rapidly and completely suppressed by treatment with infliximab. This response was accompanied by resolution of the proteinuria and stabilization of the amyloid deposits as seen on serial (123)I-labeled serum amyloid P scintigraphy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amyloidosis / complications
  • Amyloidosis / drug therapy*
  • Amyloidosis / physiopathology
  • Antibodies, Monoclonal / administration & dosage*
  • Antirheumatic Agents / administration & dosage*
  • Arthritis, Rheumatoid / complications
  • Arthritis, Rheumatoid / drug therapy*
  • Female
  • Humans
  • Infliximab
  • Kidney / physiology
  • Proteinuria / drug therapy*
  • Proteinuria / etiology
  • Proteinuria / physiopathology

Substances

  • Antibodies, Monoclonal
  • Antirheumatic Agents
  • Infliximab