Celiac disease in children with autoimmune thyroid disease

J Pediatr. 2001 Nov;139(5):738-40. doi: 10.1067/mpd.2001.118189.

Abstract

Ninety children and adolescents with autoimmune thyroid disease were screened for celiac disease. All 90 patients were typed for HLA antigen class I and II and for HLA-DQA1 and DQB1 heterodimers. Celiac disease and DQA1*0501, DQB1*02 were found in 7 (7.8%) patients. The prevalence of celiac disease was 1 of 13. Screening for celiac disease is recommended in children with autoimmune thyroid disease.

MeSH terms

  • Adolescent
  • Autoimmune Diseases / complications*
  • Celiac Disease / complications*
  • Celiac Disease / immunology
  • Child
  • Child, Preschool
  • Female
  • HLA-DQ Antigens
  • HLA-DR Antigens
  • Humans
  • Infant
  • Male
  • Thyroid Diseases / complications*
  • Thyroid Diseases / immunology

Substances

  • HLA-DQ Antigens
  • HLA-DR Antigens