Abstract
We performed a multicenter case-control study on incident cases of giant cell arteritis and polymyalgia, and tested for viruses known to induce multinucleated giant cells in human pathology. IgM directed against Human parainfluenza type 1 virus were shown to be significantly associated with the onset of the disease in 40% of the cases, versus 20% of the controls.
MeSH terms
-
Antibodies, Viral / blood
-
Case-Control Studies
-
France / epidemiology
-
Giant Cell Arteritis / epidemiology*
-
Giant Cell Arteritis / virology*
-
Humans
-
Incidence
-
Parainfluenza Virus 1, Human*
-
Polymyalgia Rheumatica / epidemiology*
-
Polymyalgia Rheumatica / virology*
-
Respirovirus Infections / epidemiology*
-
Respirovirus Infections / immunology
-
Seroepidemiologic Studies