CASE REPORTS
Warfarin-induced Leukocytoclastic Vasculitis: A Case Report and Review of Literature
Keywords:
warfarin,
leukocytoclastic vasculitis
2012 Volume 51 Issue 6 Pages 601-606
Details
2012 Volume 51 Issue 6 Pages 601-606
Warfarin is widely prescribed for patients with atrial fibrillation. In addition to unexpected bleeding, allergic skin reaction is one of its uncommon adverse effects. We herein report an 89-year-old man who, after taking warfarin for 4 years, suffered extensive skin eruptions. The skin biopsy disclosed leukocytoclastic vasculitis. The causal relationship between skin lesions and warfarin was confirmed after re-challenge of warfarin. A literature review revealed only 13 such cases reported from 1980 to 2011. Clinicians should be aware of this potential adverse effect of warfarin.
