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Abstract
The measurement of the degradation product of the C-telopeptide of type I collagen in serum (s-βCTX) has been evaluated in the form of an automated chemiluminometric assay. The between-day coefficients of variation ranged between 2.6 and 6.0% over the concentration range 0.12 to 3.25 μg/l. The s-βCTX value correlated well with alternative serum C-telopeptide (r = 0.983) and urine deoxypyridinoline (r = 0.729) measurements. A significant inverse correlation was found between the s-βCTX measurement and creatinine clearance in patients with renal disease.
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Published Online: 2005-06-01
Published in Print: 2000-11-12
Copyright © 2000 by Walter de Gruyter GmbH & Co. KG
