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Antifungal defense turns 17

Fungal recognition occurs partially through the C-type lectin dectin-1. New studies show that dectin-mediated immune recognition of Candida albicans induces the differentiation of interleukin 17–producing T helper cells that express chemokine receptors characteristic of mucosal homing.

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Figure 1: Dectins and TLRs induce distinct T helper cell responses.

Kim Caesar

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Palm, N., Medzhitov, R. Antifungal defense turns 17. Nat Immunol 8, 549–551 (2007). https://doi.org/10.1038/ni0607-549

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