MiscellaneousRelapsing Polychondritis in the Department of Defense Population and Review of the Literature
Section snippets
Materials and Methods
We performed a retrospective electronic medical record (EMR) review, with approval by the Brooke Army Medical Center Institutional Review Board, for all patients diagnosed with RPC, within the DoD beneficiary population between January 2004 and December 2009. The International Classification of Diseases, ninth Revision (ICD-9) diagnostic code, 733.9 polychondritis (atrophic, chronic, relapsing), was used to search the centralized DoD database to identify these patients. During the specified
Results
There were 50 patients diagnosed with RPC in the DoD between January 2004 and December 2009 based on the EMR. These 50 charts were reviewed and 43 patients met the study inclusion criteria. Thirty patients met McAdam's diagnostic criteria and an additional 13 met criteria for partial RPC. Seven patients were excluded, as the patients were erroneously identified on a single visit as having RPC. Of the 7 excluded patients, 1 had biopsy-proven Wegener's granulomatosis, 1 had trauma to the
Discussion
RPC is a rare autoimmune disease characterized by recurrent inflammation of cartilaginous structures. The disease frequently presents with a sudden onset, although the presenting features are variable. The clinical manifestations and biopsy findings of this disease were first classified by McAdam and colleagues (5); the criteria for diagnosis have been modified to accommodate different presentations of disease and limit the need for biopsy (Table 1). McAdam's clinical features include bilateral
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Michael J. Morras is on the speakers bureau for Pfizer/Boehringer-Ingelheim. The authors have no conflicts of interest to disclose.
“The opinions in this manuscript do not constitute endorsement by Brooke Army Medical Center, the U.S. Army Medical Department, the U.S. Army Office of the Surgeon General, the Department of the Army, Department of Defense or the U.S. Government of the information contained therein.”