The case for hepatitis C arthritis
Section snippets
Methods
A survey of the literature pertaining to arthritis in the context of hepatitis C was undertaken. The MEDLINE database was searched between 1989 and June 2003 for key words “hepatitis C” intersecting with “arthritis.” In addition, other articles and abstracts of work presented at scientific congresses relevant to the topic at hand were reviewed and brought to bear. Except for the earliest descriptions of arthritis in association with hepatitis C, case reports were largely ignored, and the work
Discussion
Since 1989, data have been steadily accumulating in support of the existence of a distinct chronic arthritis in association with chronic HCV infection. Although this arthritis may be difficult to distinguish from other common chronic arthropathies, most notably RA, it is important to consider this arthropathy in the differential diagnosis of every newly presenting oligo- or polyarthritis. Because of significant differences in treatment strategies between RA and HCV arthropathy, future research
Itzhak Rosner, MD: Director of Rheumatology, Bnai Zion Medical Center, Senior Clinical Lecturer, Technion-Faculty of Medicine, Haifa, Israel
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2017, Seminars in Arthritis and RheumatismCitation Excerpt :These manifestations range from non-specific symptoms such as fatigue to autoimmune and lymphoproliferative disorders. HCV-associated inflammatory arthritis has been described in several reports [4]. This form of arthritis can be difficult to distinguish from rheumatoid arthritis (RA), given that ~40–75% of patients with chronic HCV infection have a positive rheumatoid factor (RF) [5–8].
Itzhak Rosner, MD: Director of Rheumatology, Bnai Zion Medical Center, Senior Clinical Lecturer, Technion-Faculty of Medicine, Haifa, Israel
Michael Rozenbaum, MD: Assistant Director of Rheumatology, Bnai Zion Medical Center, Senior Clinical Lecturer, Technion-Faculty of Medicine, Haifa, Israel
Elias Toubi, MD: Director, Clinical Immunology, Bnai Zion Medical Center, Senior Clinical Lecturer, Technion-Faculty of Medicine, Haifa, Israel
Aharon Kessel, MD: Senior Physician, Clinical Immunology, Bnai Zion Medical Center, Haifa, Israel
Jochanan E. Naschitz, MD: Director, Internal Medicine A, Bnai Zion Medical Center, Associate Professor of Medicine, Technion-Faculty of Medicine, Haifa, Israel
Eli Zuckerman, MD: Director, Hepatology Unit, Bnai Zion Medical Center, Senior Clinical Lecturer, Technion-Faculty of Medicine, Haifa, Israel.