4Osteoarthritis
Section snippets
Case definitions
The major purposes of case definitions are to distinguish between individuals who have the disease from those who do not and to promote comparability between different research studies. Case-definition methods need to be distinguished from diagnostic criteria, which are used in clinical practice to differentiate between different types of illness to determine the appropriate management strategy and to enhance communication among the professionals. In research settings, medical diagnosis can
Mortality
Osteoarthritis is not regarded as a fatal disease and only a handful of studies have examined mortality among individuals with osteoarthritis. In 2007, diseases of the musculoskeletal system were reported as the underlying cause of death in less than 1% of all registered deaths in Australia. A further 3% of registered deaths had diseases of the musculoskeletal system as a contributing or associated cause of death [24]. The standardised death rate for arthritis and musculoskeletal diseases has
Prevalence
Internationally, prevalence estimates for osteoarthritis show wide variability depending on the age and sex of the studied population, the method of case identification used and the specificity of joint sites included. There have only been a few, large, population-based surveys that have included a radiographic examination of the hip or knee allowing a case definition of symptomatic knee or hip osteoarthritis, if pain is present in a joint with radiographically evident osteoarthritis. As
Risk factors
The aetiology of osteoarthritis is a complex process and is subject to ongoing investigation [49], [50], [51]. It has been suggested that disease process in osteoarthritis reflects “an age-related dynamic reaction pattern of a joint in response to insult or injury” ([10], p. 3), with a wide range of systemic, genetic, biomechanical and environmental factors contributing to the development of this condition [52]. The results suggest that the relative importance of the identified risk factors
Summary
The research presented in this article identifies osteoarthritis of the hip and knee as a substantial and increasing burden on society. Several gaps in the current understating of the burden of osteoarthritis have also been identified, including osteoarthritis prevalence and mortality. The lack of uniformity in case definitions used to identify cases of osteoarthritis in epidemiological studies, along with differences in survey methodology, make it difficult to draw reliable conclusions about
References (109)
- et al.
Osteoarthritis: epidemiology
Best Pract Res Clin Rheumatol
(2006) - et al.
Epidemiologic studies for osteoarthritis: new versus conventional study design approaches
Rheum Dis Clin North Am
(2004) - et al.
Clinical validation of self-reported osteoarthritis
Osteoarthritis Cartilage
(1998) - et al.
Nonsteroidal anti-inflammatory drug-associated gastropathy: incidence and risk factor models
Am J Med
(1991) - et al.
Severe chronic pain is associated with increased 10 year mortality. A cohort record linkage study
EuropJ Pain
(2010) - et al.
Mortality, morbidity, and 1-year outcomes of primary elective total hip arthroplasty
J Arthroplasty
(2002) - et al.
Pathogenesis and management of pain in osteoarthritis
Lancet
(2005) - et al.
Osteoarthritis and the postmenopausal woman: Epidemiological, magnetic resonance imaging, and radiological findings
Semin Arthritis Rheum
(2004) - et al.
What is the evidence that osteoarthritis is genetically determined?
Baillieres Clin Rheumatol
(1997) - et al.
The contribution of genes to osteoarthritis
Med Clin North Am
(2009)
Rheumatic disease aspects of leg length inequality
Seminars in Arthritis and Rheumatism
Prevalence and risk factors for knee osteoarthritis in elderly Japanese men and women
J Orthop Sci
Genetic influence on the progression of radiographic knee osteoarthritis: a longitudinal twin study
Osteoarthritis Cartilage
Two-year prospective longitudinal study exploring the factors associated with change in femoral cartilage volume in a cohort largely without knee radiographic osteoarthritis
Osteoarthritis Cartilage
Epidemiology of musculoskeletal impairments and associated disability
Am J Public Health
Trends in physician-diagnosed osteoarthritis incidence in an administrative database in British Columbia, Canada, 1996-1997 through 2003-2004
Arthritis Rheum
The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study
Arthritis Rheum
Obesity and osteoarthritis in knee, hip and/or hand: an epidemiological study in the general population with 10 years follow-up
BMC Musculoskelet Disord
Good reliability, questionable validity of 25 different classification criteria of knee osteoarthritis: a systematic appraisal
J Clin Epidemiol
Validity, reliability, and applicability of seven definitions of hip osteoarthritis used in epidemiological studies: a systematic appraisal
Ann Rheum Dis
Descriptive epidemiology of osteoarthritis in British Columbia, Canada
J Rheumatol
Perceptual variation in categorizing individuals according to American College of Rheumatology classification criteria for hand, knee, and hip osteoarthritis (OA): observations based on an Australian Twin Registry study of OA
J Rheumatol
Classification criteria in rheumatic diseases: a review of methodologic properties
Arthritis Rheum
Clinical classification criteria for knee osteoarthritis: performance in the general population and primary care
Ann Rheum Dis
Validity and reliability of three definitions of hip osteoarthritis: cross sectional and longitudinal approach
Ann Rheum Dis
Association between pain in the hip region and radiographic changes of osteoarthritis: results from a population-based study
Rheumatology (Oxford)
A longitudinal study of the effect of spinal degenerative disease on bone density in the elderly
J Rheumatol
Can comorbidity be measured by questionnaire rather than medical record review?
Med Care
Quality of selfreport data: a comparison of older and younger chronically ill patients
J Gerontol
Obesity and prevalence of chronic diseases in the 1999-2000 Italian National Health Survey
BMC Public Health
Prevalence and burden of osteoarthritis: results from a population survey in Norway
J Rheumatol
Comparison of clinical and self-reported diagnosis for rheumatology outpatients
Annals of the Rheumatic Diseases
Do people facing joint replacement surgery for osteoarthritis actually know they have osteoarthritis?
Intern Med J
The validity and heritability of self-report osteoarthritis in an Australian older twin sample
Twin Res
Arthritis and mortality in the epidemiological follow-up to the National Health and Nutrition Examination Survey I
Bulletin of the New York Academy of Medicine
Osteoarthritis of finger joints in Finns aged 30 or over: prevalence, determinants, and association with mortality
Ann Rheum Dis
Decreased survival with increasing prevalence of full-body, radiographically defined osteoarthritis in women
Am J Epidemiol
Pharmacist interventions in geriatric nursing facility NSAID therapy: a one-year follow-up study of costs and outcomes
Consult Pharm
Non-steroidal antiinflammatory drugs and the risk of acute myocardial infarction
Basic Clin Pharmacol Toxicol
Deaths from arthritis and other rheumatic conditions, United States, 1979-1998
J Rheumatol
Mortality after elective total hip arthroplasty in elderly Americans
Clin Orthop Relat Res
An update on the epidemiology of knee and hip osteoarthritis with a view to prevention
Arthritis & Rheumatism
Comparison of the prevalence of knee osteoarthritis between the elderly Chinese population in Beijing and whites in the United States: The Beijing Osteoarthritis Study
Arthritis Rheum
Prevalence and risk factors for knee osteoarthritis in Huang-Pu District, Shanghai, China
Rheumatol International
The high prevalence of knee osteoarthritis in a rural Chinese population: The Wuchuan OA Study
Arthritis Rheum
Prevalence of symptomatic knee, hand, and hip osteoarthritis in Greece
The ESORDIG study. J Rheumatol
Associations of radiological osteoarthritis of the hip and knee with locomotor disability in the Rotterdam study
Ann Rheum Dis
Prevalence of Knee and Hip Osteoarthritis and the Appropriateness of Joint Replacement in an Older Population
Arch Intern Med
Prevalence of knee osteoarthritis in the United States: arthritis data from the Third National Health and Nutrition Examination Survey 1991-94
J Rheumatol
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Formerly, Centre for Rheumatic Diseases, University of Melbourne.